Controlling synaptic strength diversity in hippocampal neurons
This seminar is going to be locked in the Jerome L. Greene Science Focus on Columbia’s Manhattanville campus (ninth floor lecture hall). Columbia University’s Intercampus Taxi is the easiest method to travel between campuses.
Synapses would be the fundamental nodes of knowledge transmission within the brain. The effectiveness of synaptic transmission, known as synaptic strength and it is use-dependent changes are very important for the way the mind perceives the atmosphere, learns and stores recollections. The highly diverse synaptic strengths present in confirmed connection in a particular moment within the hippocampal circuit may therefore reflect varied information coding as well as on-going learning connected with hippocampal-dependent tasks. However, cellular and molecular basis through which synaptic strength diversity arises, that’s, how synaptic strengths are positioned and controlled across a synapse population continue to be clarified. Dr. Goda has addressed this by analyzing the interaction between multiple synapses of hippocampal neurons using a mix of electrophysiology and imaging approaches. She and her team provide evidence for any novel cellular mechanism involving glial cells in controlling the heterogeneity of synaptic strengths across inputs received by single hippocampal neurons. Their findings underscore the function for glia in orchestrating synaptic transmission qualities across a synapse population.
Dr. Goda received her BSc degree in the College of Toronto, then transported out her PhD operate in the Biochemistry Department at Stanford College. After her postdoctoral work on the Salk Institute, she became a member of the school of Biology Division, College of California, North Park in 1997. She gone to live in the United kingdom in 2002 like a Senior Group Leader within the MRC Laboratory for Molecular Cell Biology at College College London. This Year, she moved to Japan to setup an organization in RIKEN Brain Science Institute, a predecessor to RIKEN CBS. Current research efforts in her own laboratory concentrate on the regulating synaptic microcircuits within the hippocampus that plays a vital role in facets of memory. Her awards include Daniel X. Freedman (1998) and Distinguished Investigator (2003) Awards in the National Alliance for Research on Schizophrenia and Depression, Klingenstein Fellowship within the Neurosciences (2001-2003), and she or he was famous for her work through the Brain Science Foundation like a person receiving the 2013 Tsukahara Nakaakira Prize. She’s presently part of the Science Council of Japan, and serves around the Society for Neuroscience Program Committee and also the editorial boards of journals including Cell, Neuron, eLife, and Trends in Neurosciences.
Individuals who would like to satisfy the speaker stay should contact Heike Blockus (Polleux Lab). For general queries please contact programs@zi.columbia.edu.
This seminar is going to be locked in the Jerome L. Greene Science Focus on Columbia’s Manhattanville campus (ninth floor lecture hall). Columbia University’s Intercampus Taxi is the easiest method to travel between campuses.
Synapses would be the fundamental nodes of knowledge transmission within the brain. The effectiveness of synaptic transmission, known as synaptic strength and it is use-dependent changes are very important for the way the mind perceives the atmosphere, learns and stores recollections. The highly diverse synaptic strengths present in confirmed connection in a particular moment within the hippocampal circuit may therefore reflect varied information coding as well as on-going learning connected with hippocampal-dependent tasks. However, cellular and molecular basis through which synaptic strength diversity arises, that’s, how synaptic strengths are positioned and controlled across a synapse population continue to be clarified. Dr. Goda has addressed this by analyzing the interaction between multiple synapses of hippocampal neurons using a mix of electrophysiology and imaging approaches. She and her team provide evidence for any novel cellular mechanism involving glial cells in controlling the heterogeneity of synaptic strengths across inputs received by single hippocampal neurons. Their findings underscore the function for glia in orchestrating synaptic transmission qualities across a synapse population.
Dr. Goda received her BSc degree in the College of Toronto, then transported out her PhD operate in the Biochemistry Department at Stanford College. After her postdoctoral work on the Salk Institute, she became a member of the school of Biology Division, College of California, North Park in 1997. She gone to live in the United kingdom in 2002 like a Senior Group Leader within the MRC Laboratory for Molecular Cell Biology at College College London. This Year, she moved to Japan to setup an organization in RIKEN Brain Science Institute, a predecessor to RIKEN CBS. Current research efforts in her own laboratory concentrate on the regulating synaptic microcircuits within the hippocampus that plays a vital role in facets of memory. Her awards include Daniel X. Freedman (1998) and Distinguished Investigator (2003) Awards in the National Alliance for Research on Schizophrenia and Depression, Klingenstein Fellowship within the Neurosciences (2001-2003), and she or he was famous for her work through the Brain Science Foundation like a person receiving the 2013 Tsukahara Nakaakira Prize. She’s presently part of the Science Council of Japan, and serves around the Society for Neuroscience Program Committee and also the editorial boards of journals including Cell, Neuron, eLife, and Trends in Neurosciences.
Individuals who would like to satisfy the speaker stay should contact Heike Blockus (Polleux Lab). For general queries please contact programs@zi.columbia.edu.
The Columbia Neuroscience Seminar series is really a collaborative effort of Columbia’s Zuckerman Institute, the Department of Neuroscience, the Doctorate Enter in Neurobiology and Behavior and also the Columbia Translational Neuroscience Initiative, with support in the Kavli Institute for Brain Science.
Resourse: https://zuckermaninstitute.columbia.edu/
